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KMID : 0191120110260010154
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Journal of Korean Medical Science
2011 Volume.26 No. 1 p.154 ~ p.157
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Isolated Spinal Cord Neurosarcoidosis Diagnosed by Cord Biopsy and Thalidomide Trial
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Ahn Suk-Won
Kim Kyoung-Tae
Youn Young-Chul
Kwon Oh-Sang
Kim Young-Baeg
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Abstract
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We report a case of 54-yr-old woman who presented with 4-extremities weakness and sensory changes, followed by cervical spinal cord lesion in magnetic resonance imaging. Based on the suspicion of spinal tumor, spinal cord biopsy was performed, and the histology revealed multinucleated giant cells, lymphocytes and aggregated histiocytes within granulomatous inflammation, consistent with non-caseating granuloma seen in sarcoidosis. The patient was treated with corticosteroid, immunosuppressant and thalidomide for years. Our case indicates that diagnosis of spinal cord sarcoidosis is challenging and may require histological examination, and high-dose corticosteroid and immunosuppressant will be a good choice in the treatment of spinal cord sarcoidosis, and the thalidomide has to be debated in the spinal cord sarcoidosis.
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KEYWORD
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Sarcoidosis, Neurosarcoidosis, Spinal Cord Sarcoidosis, Thalidomide
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